FORMULATION AND EVALUATION OF IN VITRO TRANSDERMAL PATCH DICLOFENAC SODIUM USING CHITOSAN POLYMER AND POLYVINYL ALCOHOL CROSS-LINKED TRIPOLYPHOSPHATE SODIUM
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چکیده
منابع مشابه
Preparation and Characterization of Maleic Anhydride Cross-Linked Chitosan-Polyvinyl Alcohol Hydrogel Matrix Transdermal Patch
Transdermal drug delivery systems are polymeric patches containing dissolved or dispersed drugs that deliver therapeutic agents at a constant rate to the human body. Matrix type transdermal patches were prepared using alprazolam as a model drug and employing the combinations of chitosan-polyvinyl alcohol (CS-PVA) cross linked with Maleic anhydride. The transdermal patches were evaluated for the...
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The present study was undertaken to develop a suitable transdermal matrix patch of Metoprolol tartrate with different proportions of polyvinyl pyrrolidone (PVP) and chitosan crosslinked with glutaraldehyde (GA). The prepared transdermal patches were subjected to different physicochemical evaluations such as thickness, tensile strength, folding endurance, drug content, swellability, surface pH, ...
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Background Newer drug delivery systems such as transdermal patches using pain relieving or modifying agents emerged as a mainstream treatment protocol for management of pain on the outpatient basis. The administration of diclofenac 100 mg in the transdermal patch in the patients having dental pain due to periapical/periodontal infections was evaluated. Materials and Methods Ninety patients of...
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Introduction: Mixed solvency is a concept of solubilization of the material. For producing new formulation, especially in the form of injection it is essential to solubilize the active pharmaceutical ingredients (API) in the solvent and that must be stable throughout the shelf life. Aqueous solubility of raw materials is important for injection formulation, but in some cases if the drug is not ...
متن کاملFormulation of Controlled Release Matrix Tablet of Diclofenac Sodium Using Cross Linked Starch Urea
The présent works aims to develop controlled release matrix tablet of diclofenac sodium with modified starch cross linked starch urea as an sustained release polymer and to evaluate the prepared dosage form for physical parameters like weight variation, hardness, friability and drug content. Cross linked starch urea is modified starch introducing desirable alterations in the starch structure so...
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ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2018
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2018.v11i8.25145